regex - How can find and replace muiti text at once? -

i have text:

the swiss army knife of sound processing tools: can convert sound files between many different file formats & audio devices, , can apply many sound effects & transformations, doing basic analysis , providing input more capable analysis , plotting tools.

example: want find: audio,sound , replace whitespace @ 1 time.
because have large text file can't find every word use find/replace , replace use replace all.

more information needed. if using windows try textpad - text editor large files

otherwise if on linux, have @ sed sed search & replace